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Table 2 Comparison of CD83-expressing and CD1a-expressing dendritic cells in tumor-free and tumor-containing sentinel lymph nodes (SLNs) by tumor grades

From: Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer

Dendritic cellsa

Tumor gradeb

 

Grade I

Grade II

Grade III

CD83-expressing cells

   

Tumor-free SLNs

   

   Number

3

11

8

   Mean (± SEM)

4.5 ± 4.5

10.2 ± 3.5

13.0 ± 2.9

   Median

0

8

16.7

   Range

0–13.4

0.4–38.4

0.4–21.8

Tumor-containing SLNs

   

   Number

3

12

8

   Mean (± SEM)

9.1 ± 2.7

4.9 ± 1.3

5.8 ± 1.8

   Median

9.2

3.3

5.5

   Range

4.4–13.6

0–14.2

0.6–15.4

P valuec

0.40

0.34

0.16

CD1a-expressing cells

   

Tumor-free SLNs

   

   Number

3

11

8

   Mean (± SEM)

57.9 ± 5.6

60.0 ± 10.5

49.0 ± 5.1

   Median

63.2

63.5

48.6

   Range

46.8–63.8

0–97.0

25.6–70.6

Tumor-containing SLNs

   

   Number

3

12

8

   Mean (± SEM)

59.0 ± 23.5

48.7 ± 8.5

80.0 ± 8.1

   Median

53.2

41.6

74.3

   Range

21.6–102.2

12.4–102.0

54.4–122.8

P value

1.0

0.41

0.01

  1. SEM, standard error of the mean. a Number of cells per high-powered field. b The grade was unknown for two tumors in the tumor-containing SLN group and for three tumors in the tumor-free SLN group. c P values determined by the Wilcoxon rank sum test comparing the number of CD83-expressing or CD1a-expressing dendritic cells in tumor-free SLNs versus tumor-containing SLNs for each tumor grade.
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