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Table 2 Comparison of CD83-expressing and CD1a-expressing dendritic cells in tumor-free and tumor-containing sentinel lymph nodes (SLNs) by tumor grades

From: Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer

Dendritic cellsa Tumor gradeb
  Grade I Grade II Grade III
CD83-expressing cells    
Tumor-free SLNs    
   Number 3 11 8
   Mean (± SEM) 4.5 ± 4.5 10.2 ± 3.5 13.0 ± 2.9
   Median 0 8 16.7
   Range 0–13.4 0.4–38.4 0.4–21.8
Tumor-containing SLNs    
   Number 3 12 8
   Mean (± SEM) 9.1 ± 2.7 4.9 ± 1.3 5.8 ± 1.8
   Median 9.2 3.3 5.5
   Range 4.4–13.6 0–14.2 0.6–15.4
P valuec 0.40 0.34 0.16
CD1a-expressing cells    
Tumor-free SLNs    
   Number 3 11 8
   Mean (± SEM) 57.9 ± 5.6 60.0 ± 10.5 49.0 ± 5.1
   Median 63.2 63.5 48.6
   Range 46.8–63.8 0–97.0 25.6–70.6
Tumor-containing SLNs    
   Number 3 12 8
   Mean (± SEM) 59.0 ± 23.5 48.7 ± 8.5 80.0 ± 8.1
   Median 53.2 41.6 74.3
   Range 21.6–102.2 12.4–102.0 54.4–122.8
P value 1.0 0.41 0.01
  1. SEM, standard error of the mean. a Number of cells per high-powered field. b The grade was unknown for two tumors in the tumor-containing SLN group and for three tumors in the tumor-free SLN group. c P values determined by the Wilcoxon rank sum test comparing the number of CD83-expressing or CD1a-expressing dendritic cells in tumor-free SLNs versus tumor-containing SLNs for each tumor grade.
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Breast Cancer Research

ISSN: 1465-542X

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