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Table 1 Features of the probands and their families analyzed for EP300 germline mutations

From: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer

    Number of tumours in the family1
Proband Proband tumour site Proband age at onset (years) Breast Ovary Bowel Pancreatic Stomach Other
0011 br 32 8 0 1 0 2 0
0017 br 70 3 0 0 0 1 0
0187 br/bil 28/39 7 0 1 0 0 0
0318 br/ov 41/46 7 2 1 0 1 1
0329 br 43 3 0 1 0 0 1
0342 br 41 2 0 0 0 1 1
0458 br 46 4 0 0 0 1 3
0580 br 44 5 1 2 0 0 1
0894 br 45 5 0 0 1 0 1
0933 br 50 4 0 0 1 0 1
0990 br 42 4 0 1 0 0 2
1018 br 66 5 0 3 0 1 8
1115 br 49 6 1 1 0 3 4
1279 br 41 4 0 2 0 0 4
1566 br 53 4 0 1 0 1 4
1853 br/bil 43/47 2 0 2 0 0 1
1890 br/stom 21/49 2 0 6 0 0 5
1934 br 49 4 0 3 0 0 3
2033 br/stom/th 37/58/59 3 0 0 0 1 1
2220 br 29 5 0 1 1 0 4
2263 br 38 4 0 4 0 0 1
4734 br 49 6 0 2 0 0 7
0001 br 37 2 0 1 0 0 0
  1. 1The number of tumors includes proband's tumors. bil, bilateral breast cancer; br, breast cancer; ov, ovarian cancer; stom, stomach cancer; th, thyroid cancer.
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