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Table 3 Fertility and superovulation data in the βERKO female mice

From: Estrogen receptor transcription and transactivation Estrogen receptor knockout mice: what their phenotypes reveal about mechanisms of estrogen action

 

Continuous mating results

Superovulation results

Genotype

n

Litters/female

Pups/litter

n

Mean

Range

Wild type

6

2.8 ± 0.4

8.8 ± 2.5

10

33.7 ± 4.8

9-57

Heterozygous

ND

ND

ND

11

52.5 ± 5.7*

20-77

βERKO

11

1.7 ± 1.0*

3.1 ± 1.8**

11

6.0 ± 1.5*

0-13

  1. Data presented as mean ± standard error of the mean. ERKO, Estrogen receptor knockout; ND, not determined. Reproduced from Couse and Korach [5**]. * P < 0.05 and ** P < 0.001 Student's two tailed t-test versus wild type.