Figure 2From: Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neuin a murine mammary carcinoma modelTumor growth in 10 mice treated with doxorubicin (DOX) and the viral replicon gene vaccine Venezuelan equine encephalitis virus replicon particles (VRP)-neu containing the gene for neu (lower line), compared with eight mice treated with DOX and the negative control viral replicon gene vaccine VRP-hemagglutinin (HA) lacking the gene for neu (upper line). DOX alone (â–¿) or saline alone (â–¼) were also tested in groups of eight and 10 mice, respectively, and the values are shown for day 35.Back to article page