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Table 3 Multivariate survival analyses (Cox regression model) in node-positive breast cancer (n = 77)

From: Hypoxia-inducible factor 1 alpha in high-risk breast cancer: an independent prognostic parameter?

  Distant metastasis-free survival Disease-free survival Overall survival
  P Relative risk (95% confidence interval) P Relative risk (95% confidence interval) P Relative risk (95% confidence interval)
Age       
   > 50 years versus < 50 years 0.14 0.50 (0.20–1.26) 0.20 0.56 (0.23–1.36) 0.13 0.43 (0.15–1.29)
T stage       
   T3/T4 versus T1/T2 0.01 3.16 (1.32–7.58) 0.03 2.57 (1.08–6.11) 0.03 3.03 (1.08–8.51)
Estrogen receptor       
   Positive versus negative 0.32 0.64 (0.26–1.56) 0.18 0.54 (0.22–1.33) -  
Number of positive lymph nodes       
   4+ versus 1–3 0.02 4.06 (1.17–14.01) 0.02 4.42 (1.28–15.32) 0.16 3.00 (0.64–13.97)
hif-1α expression       
   Yes versus no 0.18 1.94 (0.73–5.17) 0.30 1.68 (0.62–4.47) 0.09 2.66 (0.83–8.51)
  1. hif-1α, hypoxia-inducible factor 1 alpha.