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Table 4 Hypothetical data from the counter-matched sets depicted in Fig. 2

From: Study design: Evaluating gene–environment interactions in the etiology of breast cancer – the WECARE study

Set no. (setno) Subject ID (id) Case = 1/control = 0 (cc) RRT status (rrt) Number sampled from RRT stratum (m_rrt) Total in RRT stratum (n_rrt) True RT status (true_rt) Radiation dose (rad_dose) ATM mutation carrier status (atm) Chemotherapy (chemo)
1 12 0 0 1 16 0 0 0 1
1 3 1 1 2 11 1 250 0 1
1 16 0 1 2 11 1 40 0 0
2 5 1 0 1 16 0 0 1 1
2 25 0 1 2 10 1 110 0 0
2 22 0 1 2 10 1 100 0 1
3 18 0 0 1 12 1 220 0 1
3 9 1 1 2 8 1 40 0 1
3 24 0 1 2 8 1 6 1 0
4 23 1 0 1 11 0 0 0 1
4 2 0 1 2 7 1 170 1 0
4 19 0 1 2 7 0 0 0 0
5 1 0 0 1 1 0 0 0 1
5 2 1 1 2 1 1 250 0 1
  1. The structure of the data is as in a standard matched case-control study, but the numbers in each of the sampling strata (n_rrt) are required for analysis. The radiation dose is defined as the absorbed radiation dose (cGy) to quadrant in the contralateral breast where the case's tumor was located. Mutation carrier status is recorded as 0 = non-carrier, 1 = carrier. The status of chemotherapy administration as gathered from medical record review is shown (0 = no chemo, 1 = chemo). ID, identification number; RRT, indicator of radiation therapy as derived from registry records (registry RT; 0 = RRT-; 1 = RRT+); RT, status of radiation therapy administration as gathered from medical record review (True RT; 0 = TRT-, 1 = TRT+).