| | | | | Counter-matching |
|---|
| | | Random sampling | CM 1:2 | CM 2:1 |
|---|
2 Gy rate ratio | Alla
| NCC 3 | NCC 4 | PN = 100%, PP = 100% | PN = 90%, PP = 90% | PN = 100%, PP = 100% |
|---|
1.4 | 79 | 61 | 63 | 70 | 67 | 63 |
1.5 | 87 | 69 | 78 | 84 | 80 | 78 |
1.6 | 97 | 86 | 93 | 95 | 92 | 92 |
1.7 | 100 | 95 | 97 | 99 | 96 | 97 |
- CM 1:2, counter-matched design in which one member of the triplet is registry radiation treatment negative (RRT-) and two are registry radiation treatment positive (RRT+); CM 2:1, counter-matched design in which two members of the triplet are RRT- and one is RRT+; NCC 3, nested case-control study in which each case is randomly matched to two controls; NCC 4, nested case-control study in which each case is randomly matched to three controls; PN, predictive negative value; PP, predictive positive value. aFull cohort power where radiation dose is available for all controls in the risk set and used in the analysis; this is the upper limit on any case-control analysis.
