Table 5 Multivariate Cox regression models for disease-free survival and overall survival in invasive lobular carcinoma patients
From: Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome
| Â | DFS | OS | ||
|---|---|---|---|---|
Parameter | RR (95% CI) | P | RR (95% CI) | P |
Nodes | Â | Â | Â | Â |
   0 | 1 | <0.0001 | 1 | <0.0001 |
   1–3 | 2.2 (1.6–3.2) |  | 1.4 (1.1–1.9) |  |
   >3 | 4.1 (2.9–5.7) |  | 2.2 (1.7–2.9) |  |
Tumor size (cm) | Â | Â | Â | Â |
   ≤2 | 1 | <0.0001 | 1 | <0.0001 |
   >2 | 1.9 (1.4–2.6) |  | 1.6 (1.3–2.1) |  |
Age (years) | Â | Â | Â | Â |
   ≤50 | - | NS | 1 | <0.0001 |
   >50 | - |  | 2.3 (1.7–3.1) |  |
S-phase | Â | Â | Â | Â |
   Low | 1 | 0.002 | 1 | <0.0293 |
   Intermediate–high | 1.7 (1.3–2.2) |  | 1.3 (1.0–1.6) |  |
PgR | Â | Â | Â | Â |
   Positive | 1 | 0.003 | - | NS |
   Negative | 1.5 (1.1–1.9) |  | - |  |
ER | Â | Â | Â | Â |
   Positive | - | NS | 1 | 0.0006 |
   Negative | - |  | 1.9 (1.3–2.8) |  |
Ploidy | Â | Â | Â | Â |
   Diploid | 1 | 0.03 | - | NS |
   Aneuploid | 1.7 (1.3–2.2) |  | - |  |