Table 1 Patients and tumor biological characteristics by histologic group
From: Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome
| Â | ILC | IDC | P |
|---|---|---|---|
Patients (n) | 4140 | 45169 | Â |
Tumor size | Â | Â | Â |
   Number with data | 3962 | 43827 |  |
   ≤2 cm (%) | 46.1 | 51.3 |  |
   >2 and ≤5 cm (%) | 39.8 | 39.5 | <0.0001 |
   >5 cm (%) | 14.0 | 9.1 |  |
Age | Â | Â | Â |
   Number with data | 3501 | 38436 |  |
   ≤50 years | 19.4 | 27.8 | <0.0001 |
>50 years | 80.6 | 72.2 | Â |
Positive lymph nodes | Â | Â | Â |
   Number with data | 3891 | 43066 |  |
   0 | 57.3 | 58.0 | NS |
   ≥1 | 42.7 | 42.0 |  |
Estrogen receptor | Â | Â | Â |
   Number tested | 4140 | 45169 |  |
   Positive (%) | 92.7 | 81.2 | <0.0001 |
Progesterone receptor | Â | Â | Â |
   Number tested | 4075 | 44307 |  |
   Positive (%) | 67.4 | 60.2 | <0.0001 |
Ploidy | Â | Â | Â |
   Number tested | 3763 | 40123 |  |
   Diploid (%) | 69.8 | 43.6 | <0.0001 |
S-phase fraction | Â | Â | Â |
   Number tested | 3339 | 34620 |  |
   Low | 68.6 | 46.7 |  |
   Intermediate | 19.2 | 21.9 | <0.0001 |
   High | 12.2 | 31.4 |  |
p53 | Â | Â | Â |
   Number tested | 86 | 1009 |  |
   Negative (normal; %) | 74.4 | 46.5 | <0.0001 |
HER-2 | Â | Â | Â |
   Number tested | 263 | 2909 |  |
   Negative (%) | 89.3 | 75.6 | <0.0001 |
Epidermal growth factor receptor | Â | Â | Â |
   Number tested | 203 | 2366 |  |
   Negative (%) | 94.1 | 80.7 | <0.0001 |