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Table 1 Patients and tumor biological characteristics by histologic group

From: Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome

  ILC IDC P
Patients (n) 4140 45169  
Tumor size    
   Number with data 3962 43827  
   ≤2 cm (%) 46.1 51.3  
   >2 and ≤5 cm (%) 39.8 39.5 <0.0001
   >5 cm (%) 14.0 9.1  
Age    
   Number with data 3501 38436  
   ≤50 years 19.4 27.8 <0.0001
>50 years 80.6 72.2  
Positive lymph nodes    
   Number with data 3891 43066  
   0 57.3 58.0 NS
   ≥1 42.7 42.0  
Estrogen receptor    
   Number tested 4140 45169  
   Positive (%) 92.7 81.2 <0.0001
Progesterone receptor    
   Number tested 4075 44307  
   Positive (%) 67.4 60.2 <0.0001
Ploidy    
   Number tested 3763 40123  
   Diploid (%) 69.8 43.6 <0.0001
S-phase fraction    
   Number tested 3339 34620  
   Low 68.6 46.7  
   Intermediate 19.2 21.9 <0.0001
   High 12.2 31.4  
p53    
   Number tested 86 1009  
   Negative (normal; %) 74.4 46.5 <0.0001
HER-2    
   Number tested 263 2909  
   Negative (%) 89.3 75.6 <0.0001
Epidermal growth factor receptor    
   Number tested 203 2366  
   Negative (%) 94.1 80.7 <0.0001
  1. IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma.