Analysis of DNA ploidy of LM38-LP (a), LM38-HP (b) and LM38-D2 (c) cells. (a) Whereas islets of epithelial cells were hypotriploid (1), large spindle cells, probably of myoepithelial phenotype, made up a large hypertetraploid subpopulation (2). (b) The main small spindle cell subpopulation was hypotriploid (1), similarly to the islets of epithelial cells in LM38-LP cultures. A small peak of a hypertetraploid subpopulation was also found (2). (c) The myoepithelial LM38-D2 clone was made up of two subpopulations, either hypertetraploid (2) or even with a higher DNA index (3).