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Table 2 The relationship between gene expression pattern and gene function in the seven-point lactation/involution time course

From: Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

Cluster Transcripts Biological process Molecular function
Inv1 292 Transport Immunity
   Cell surface signal Enzyme
   Intracellular signal Structural
    Growth factors
Inv2 153 Transport Enzyme
Inv3 336 Biogenesis Apoptosis
   Metabolism Enzyme
   Development Nucleic acid
    Signal transducer
    Structural
Inv4 420 Cell adhesion Apoptosis
   Cell surface signal Immuntiy
   ECM and morphogenesis Enzyme
    Signal transducer
    Structural
    Cytokine
Lac1 374 Intracellular signal  
Lac2 163 Biogenesis Enzyme
   Metabolism Nucleic acid
   Transport Transport
   ECM and Morphogenesis  
Lac3 188 Cell adhesion Signal transducer
   Transport Transport
   Development Cytokine
    Growth factors
  1. Transcripts representing genes with known function were classified by molecular function and biological process, according to the ontological definitions of the Gene Ontology Consortium. The total numbers of known transcripts classified in this way are shown for each cluster. A statistical test for nonrandom distribution of these functional groups (taking into account the total number of transcripts in each category) was performed on each cluster using Onto-Express. All statistically significant associations (corrected P < 0.05) are listed for each cluster using the same ontological definitions used in Table 1 and available on GeNet. Additional information on the details of these significant associations and a graphical representation of all ontologies are available as Additional files 2 and 5. ECM, extracellular matrix.