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Figure 3 | Breast Cancer Research

Figure 3

From: Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer

Figure 3

Kaplan–Meier analysis of disease-free survival of breast cancer patients dependent on the expression of mRNA coding for oestradiol metabolising enzymes. (a) CYP19 (aromatase) using the conventional, adipose tissue-specific first exon (curve 1), abnormally using the ovarian-specific first exon (curve 2), and with the 0-null expression (curve 0). (b) Steroid sulfatase with expression below (curve 1) and above (curve 2) the median. (c) Oestrogen receptor (ER)α below (curve 1) and above (curve 2) the median. (d) ERβ below (curve 2) and above (curve 1) the median.

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Breast Cancer Research

ISSN: 1465-542X

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