Table 2 Effect of synthetic estrogens and progestins on mammary carcinogenesis
From: Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments
Treatment | Duration | Mammary cancer incidence | Rats with mammary cancer (%) | Average number of cancers per rat |
|---|---|---|---|---|
Control | 3 weeks | 9/12 | 75 | 1.5 ± 0.3 |
100 μg eE + 30 mg megesterol | 3 weeks | 3/13* | 23 | 0.3 ± 0.2* |
30 mg tamoxifen + 30 mg progesterone | 3 weeks | 7/12 | 58 | 0.9 ± 0.3 |
100 μg eE + 30 mg megesterol | 1 week | 5/13 | 38 | 0.4 ± 0.1* |
100 μg eE + 30 mg norethindrone | 1 week | 3/12* | 25 | 0.2 ± 0.1* |