Table 3 BRCA1 and BRCA2 mutations by sex, age at disease diagnosis and presence of breast/ovarian cancer in first-/second-degree relative(s) in the total population of 136 breast/ovarian cancer probands analyzed
From: BRCA1 and BRCA2 mutations in central and southern Italian patients
BRCA1 | BRCA2 | Total | ||||
|---|---|---|---|---|---|---|
Characteristics of patients | Positive (%) | Negative | Positive (%) | Negative | Positive (%) | Negative |
Age | ||||||
50 years or under | 4 (6) | 64 | 1 (1) | 67 | 5 (7) | 63 |
Older than 50 years | 1 (1) | 67 | 5 (7) | 63 | 6 (9) | 62 |
Sex | ||||||
Female | 5 (4) | 112 | 4 (3) | 113 | 9 (8) | 108 |
Male | 0 (0) | 19 | 2 (10) | 17 | 2 (10) | 17 |
Cancer in relative(s) | ||||||
Yes | 4 (6) | 66 | 4 (6) | 66 | 8 (11) | 62 |
No | 1 (1) | 65 | 2 (3) | 64 | 3 (4) | 63 |