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Table 1 Breast cancer prevention trials

From: Future possibilities in the prevention of breast cancer: Breast cancer prevention trials

Trial

Population

Agent (versus placebo), dose (mg/day)

Intended duration of treatment (years)

RMH [5*]

High risk Family history

Tamoxifen, 20

5-8

NSABP [3*]

1.6% 5-year risk

Tamoxifen, 20

5

Italian [6*]

Normal Risk Hysterectomy

Tamoxifen, 20

5

IBIS

>Twofold risk

Tamoxifen, 20

5

MORE [7*]

Normal risk Osteoporotic Postmenopausal

Raloxifene, 60 or 120

3