From: Future possibilities in the prevention of breast cancer: Breast cancer prevention trials
Trial | Population | Agent (versus placebo), dose (mg/day) | Intended duration of treatment (years) |
---|---|---|---|
RMH [5*] | High risk Family history | Tamoxifen, 20 | 5-8 |
NSABP [3*] | 1.6% 5-year risk | Tamoxifen, 20 | 5 |
Italian [6*] | Normal Risk Hysterectomy | Tamoxifen, 20 | 5 |
IBIS | >Twofold risk | Tamoxifen, 20 | 5 |
MORE [7*] | Normal risk Osteoporotic Postmenopausal | Raloxifene, 60 or 120 | 3 |