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Table 3 Final multivariate model of breast cancer specific survival

From: A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

Variable n Deaths due to breast cancer (n) Hazard ratio (95% CI) P
BRCA1 mutation     
   No mutation 397 52 1.00 0.01
BRCA1 37 14 2.39 (1.20–4.75)  
Tumor size     
   < 2 cm 333 39 1.00 0.003
   ≥ 2 cm 101 27 2.19 (1.30–3.67)  
Axillary node     
   Negative 280 31 1.00 0.03
   Positive 154 35 1.78 (1.07–2.96)  
Age (years)     
   < 50 146 34 1.00 0.02
   ≥ 50 288 32 0.55 (0.33–0.92)  
  1. CI, confidence interval