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Table 3 Final multivariate model of breast cancer specific survival

From: A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

Variable

n

Deaths due to breast cancer (n)

Hazard ratio (95% CI)

P

BRCA1 mutation

    

   No mutation

397

52

1.00

0.01

BRCA1

37

14

2.39 (1.20–4.75)

 

Tumor size

    

   < 2 cm

333

39

1.00

0.003

   ≥ 2 cm

101

27

2.19 (1.30–3.67)

 

Axillary node

    

   Negative

280

31

1.00

0.03

   Positive

154

35

1.78 (1.07–2.96)

 

Age (years)

    

   < 50

146

34

1.00

0.02

   ≥ 50

288

32

0.55 (0.33–0.92)

 
  1. CI, confidence interval