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Table 2 Univariate analysis of factors influencing breast cancer specific survival

From: A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

Variable

n

Breast cancer deaths (n)

P

BRCA mutation

   

   Any

56

18

0.0002

   None

439

61

 

BRCA1 mutation

   

   Mutation present

43

16

< 0.0001

   Mutation absent

439

61

 

BRCA2 mutation

   

   Mutation present

14

2

0.76

   Mutation absent

439

61

 

Tumor size

   

   ≤ 2 cm

360

41

< 0.0001

   > 2 cm

111

31

 

Axillary node

   

   Negative

290

31

< 0.0001

   Positive

172

44

 

Estrogen receptor

   

   Positive

210

28

0.01

   Negative

127

31

 

Age at diagnosis (years)

 

   < 50

169

42

< 0.0001

   ≥ 50

326

37

 

Chemotherapy

   

   Yes

187

48

< 0.0001

   No

279

30

 

Tamoxifen

   

   Yes

208

28

0.14

   No

237

47