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Table 2 Univariate analysis of factors influencing breast cancer specific survival

From: A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

Variable n Breast cancer deaths (n) P
BRCA mutation    
   Any 56 18 0.0002
   None 439 61  
BRCA1 mutation    
   Mutation present 43 16 < 0.0001
   Mutation absent 439 61  
BRCA2 mutation    
   Mutation present 14 2 0.76
   Mutation absent 439 61  
Tumor size    
   ≤ 2 cm 360 41 < 0.0001
   > 2 cm 111 31  
Axillary node    
   Negative 290 31 < 0.0001
   Positive 172 44  
Estrogen receptor    
   Positive 210 28 0.01
   Negative 127 31  
Age at diagnosis (years)  
   < 50 169 42 < 0.0001
   ≥ 50 326 37  
Chemotherapy    
   Yes 187 48 < 0.0001
   No 279 30  
Tamoxifen    
   Yes 208 28 0.14
   No 237 47