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Figure 2 | Breast Cancer Research

Figure 2

From: Cell clusters overlying focally disrupted mammary myoepithelial cell layers and adjacent cells within the same duct display different immunohistochemical and genetic features: implications for tumor progression and invasion

Figure 2

Myoepithelial cell layer disruptions and overlying small estrogen receptor (ER)-negative cell clusters (< 15 cells) in ER-positive ductal carcinoma in situ (DCIS). (a) H & E staining of a large duct with DCIS, 100×; (b) the adjacent section of (a) immunostained, 100×; (c) a higher magnification of (a); (d) a higher magnification of (b). The myoepithelial cell layer disruption and the overlying ER-negative cells are identified with an arrow.

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