Table 5 Disease-free survival of 110 patients with primary invasive breast carcinoma
From: aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer
Univariate analysis | Multivariate analysis (Cox) | ||||||
|---|---|---|---|---|---|---|---|
Parameter | Value | RR | 5-year survival rate (Rothman's 95% CI) | P | RR | 95% CI | P |
aHIF | REx ≤ 0.35 | 1 | 80% (70–87) | 0.0038 | 1 | 1.5–7.4 | 0.0016 |
REx > 0.35 | 2.8 | 45% (26–66) | 3.3 | ||||
SBR grade | 1 | 0 | 100% | 0.023 | 1 | 1.1–4.6 | 0.0032 |
2 | 1 | 76% (62–87) | 2.3 | 1.2–21.4 | |||
3 | 2 | 57% (39–73) | 5.1 | ||||
Oestrogen receptors | + | 1 | 82% (69–90) | 0.024 | 1 | 0.9–5.2 | n.s. |
- | 2.5 | 58% (42–72) | 2.1 | ||||
S phase | ≤ 10% | 1 | 81% (67–89) | 0.017 | 1 | 0.6–3.7 | n.s. |
>10% | 2.6 | 56% (39–71) | 1.5 | ||||