Table 2 Cancer incidence in first-degree relatives of index cases with breast cancer younger than age 41 but noBRCA1/BRCA2 germline mutation, and at least one additional case of breast cancer in a first-degree or second-degree relative

140–209

All malignant tumours

18.5

2.3

1.6–3.1

Non-170

All malignant tumours except breast

15.9

1.8

1.2–2.6

153

Large bowel

1.2

0.82

0.02–4.6

154

Rectum

0.82

2.4

0.30–8.8

162

Trachea and lung

1.5

2.0

0.42–5.9

170

Breast

2.6

5.3

2.9–9.0

171

Cervix uteri

0.39

5.1

0.62–18.5

175

Ovaries

0.50

2.0

0.05–11.0

177

Prostate

2.4

2.5

0.91–5.4

180

Kidney

0.74

2.7

0.33–9.8

181

Bladder and urinary tract

0.93

2.1

0.26–7.8

191

Skin nonmelanoma

0.50

2.0

0.05–11.2

193

Central nervous system

0.86

2.3

0.28–8.4

200 + 202

Non-Hodgkin's lymphoma

0.66

4.5

0.94–13.3