Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma

Table 1 Clinicopathological features and staining patterns of CXCR4 in breast cancer

Feature	Focal expression (n = 20)	Diffuse expression (n = 59)	P
Age (years)	47.5 ± 7.5	53.2 ± 7.5	NS
Sex
Male	0	1
Female	19	58	NS
Tumor size (cm)
T1	6	19
T2	10	33
T3	4	7	NS
Pathological type
Papillotubular	5	20
Solid tubular	1	9
Scirrhous	13	27
Others	1	3	NS
Histological grade
1	5	27
2	8	23
3	7	9	NS
Lymphatic invasion
Negative	9	31
Positive	11	28	NS
Venous invasion
Negative	15	41
Positive	5	18	NS
Estrogen receptor
Negative	6	23
Positive	12	29
Unknown	2	7	NS
Lymph node metastasis
Negative	8	33
Positive	12	26	NS
Distant metastasis
Negative	14	46
Positive	6	13	NS

The differences between the two groups were evaluated by χ² tests. NS, not significant. T1, ≤ 2.0 cm; T2, > 2.0, ≤ 5.0 cm; T3, > 5.0 cm.

ISSN: 1465-542X