Table 1 Univariate analysis of the relationship between mammaglobin expression and all studied clinical and biological variables
Variable | n | Mammaglobin > 205.78a (%) | OR | 95% CI | P |
|---|---|---|---|---|---|
Histology | |||||
Ductal + tubular | 108 | 52 (48) | 1.00 | ||
Lobular | 20 | 12 (60) | 1.62 | 0.61–4.30 | 0.332 |
Chemotherapy | |||||
No | 15 | 55 (49) | 1.00 | ||
Yes | 128 | 9 (60) | 1.58 | 0.52–4.77 | 0.412 |
Histological grade | |||||
1+2 | 60 | 32 (53) | 1.00 | ||
3 | 42 | 17 (40) | 0.60 | 0.27–1.34 | 0.203 |
Nuclear grade | |||||
1+2 | 52 | 30 (58) | 1.00 | ||
3 | 51 | 19 (37) | 0.44 | 0.19–0.98 | 0.039 |
Nodal metastasis | |||||
No | 70 | 40 (57) | 1.00 | ||
Yes | 55 | 22 (40) | 0.50 | 0.24–1.04 | 0.058 |
DNA ploidy | |||||
>1 | 68 | 27 (40) | 1.00 | ||
1 | 60 | 37 (62) | 2.44 | 1.17–5.08 | 0.014 |
Oestrogen receptor | |||||
Negative | 34 | 12 (35) | 1.00 | ||
Positive | 93 | 52 (56) | 2.33 | 1.01–5.34 | 0.040 |
Progesterone receptor | |||||
Negative | 62 | 23 (37) | 1.00 | ||
Positive | 66 | 41 (62) | 2.78 | 1.32–5.84 | 0.005 |
c-erbB-2 | |||||
Negative | 103 | 53 (51) | 1.00 | ||
Positive | 25 | 11 (44) | 0.74 | 0.31–1.79 | 0.505 |
p53 | |||||
Negative | 107 | 56 (52) | 1.00 | ||
Positive | 21 | 8 (38) | 0.56 | 0.21–1.48 | 0.235 |
Ki67 | |||||
≤ 20% | 79 | 46 (58) | 1.00 | ||
>20% | 49 | 18 (37) | 0.42 | 0.20–0.88 | 0.019 |