Adolescent diet and risk of breast cancer

Breast Cancer Research

Table 2 Relative risk (RR) of breast cancer according to quintiles (Q) of nutrient intake during high school among women born between 1922 and 1946

Nutrient	Parameter	Q₁	Q₂	Q₃	Q₄	Q₅	P for trend
Protein (g/day)	Median intake	34.9	50.1	61.3	73.3	93.5
	Multivariate RR	1.0	0.92	0.98	0.88	0.88	0.27
Animal fat (g/day)	Median intake	25.5	39.7	51.2	64.2	84.7
	Multivariate RR	1.0	0.98	0.95	0.94	1.01	0.96
Vegetable fat (g/day)	Median intake	5.4	9.3	12.2	17.8	28.3
	Multivariate RR	1.0	1.12	1.13	0.96	0.85	0.05
Monounsaturated fat (g/day)	Median intake	13.3	19.4	24.4	29.9	39.8
	Multivariate RR	1.0	1.01	0.90	0.95	0.89	0.28
Saturated fat (g/day)	Median intake	14.5	22.2	29.0	36.5	48.4
	Multivariate RR	1.0	0.92	0.94	0.86	0.98	0.82
Total fat (g/day)	Median intake	35.5	52.3	66.2	81.5	107.5
	Multivariate RR	1.0	1.11	0.86	1.0	0.92	0.32
Folate (μg/day)	Median intake	81.9	117	151	181	238
	Multivariate RR	1.0	0.92	1.01	0.89	0.86	0.21
Vitamin A (IU/day)	Median intake	2063	3457	4901	7311	11,437
	Multivariate RR	1.0	1.01	0.95	1.13	1.02	0.63
Retinol (IU/day)	Median intake	612	1001	1378	1814	5542
	Multivariate RR	1.0	1.06	0.89	1.02	1.05	0.59
Carotenoid (IU/day)	Median intake	1053	2030	3214	4832	9253
	Multivariate RR	1.0	1.14	1.08	1.16	1.10	0.65
Vitamin C (mg/day)	Median intake	24.6	40.3	62.1	91.2	121
	Multivariate RR	1.0	0.88	1.01	0.90	0.95	0.77
Vitamin D (IU/day)	Median intake	107	186	308	385	691
	Multivariate RR	1.0	0.86	0.98	0.99	0.96	0.84
Vitamin E (IU/day)	Median intake	2.20	3.30	4.10	5.20	8.10
	Multivariate RR	1.0	1.07	1.04	0.98	0.87	0.18
Dietary fiber (g/day)	Median intake	5.6	7.5	9.10	11.0	14.3
	Multivariate RR	1.0	0.84	1.01	0.89	0.78	0.09

Results are from multivariate analyses adjusted for age at diagnosis, age at menarche, menopausal status, family history, benign breast disease, adult height, parity/age at first birth, postmenopausal hormone use, body mass index at age 18, alcohol intake in 1980, and vitamin A intake, excluding supplements, in 1980 among 843 cases of breast cancer age matched 10:1 with controls.