From: Akt kinases in breast cancer and the results of adjuvant therapy
Number of patients | Rate ratio | Test for significance (P) | |
---|---|---|---|
Number of positive nodesa | |||
0 | 19 | 1.0 | |
1–3 | 119 | 4.3 | 0.000078 |
> 3 | 58 | 7.4 | |
Tumour size (mm)a | |||
≤ 20 | 89 | 1.0 | |
21–30 | 62 | 1.5 | 0.0031 |
> 30 | 45 | 2.7 | |
Aktb | |||
Akt- | 107 | 1.0 | |
Akt+ | 78 | 0.53 | 0.038 |
Radiotherapy/chemotherapyb | |||
Radiotherapy | 86 | 1.0 | |
CMF chemotherapy | 110 | 0.91 | 0.65 |
Tamoxifenb | |||
No tamoxifen | 100 | 1.0 | |
Tamoxifen | 96 | 0.40 | 0.0010 |
Akt × tamoxifen | |||
0 | 147 | 1.0 | |
1 | 38 | 1.7 | 0.28 |