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Figure 2 | Breast Cancer Research

Figure 2

From: Expression profiling to predict outcome in breast cancer: the influence of sample selection

Figure 2

Multidimensional scaling (MDS) clustering of gene expression data from breast tumors using 58 out of 231 genes from the outcome predictor gene set identified by van 't Veer et al. [7] that were also included in our array analysis. These genes retain their predictive value in those data but not in our independent patient sample. (a) Fifty-eight primary breast tumors (training set) from the study by van't Veer et al. and (b) 44 from our array study are plotted. Tumors with a poor prognosis (distant recurrences within 6 years) are colored blue and tumors with a good prognosis (no recurrences within a follow-up period of 5–14 years) are orange. MDS displays the position of each tumor sample in a three-dimensional euclidean space, with the distance between the samples reflecting their approximate degree of correlation [11].

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