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Figure 1 | Breast Cancer Research

Figure 1

From: Progesterone receptors - animal models and cell signaling in breast cancer: Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics

Figure 1

Progesterone receptor function is required for mammary ductal side-branching and alveologenesis. (a) The salient postnatal stages of mammary gland development. Whole mounts of (b) transplanted progesterone receptor knockout (PRKO) mammary glands and (c) wild-type mammary glands taken from a nulliparous host, and (d) transplanted PRKO mammary glands and (e) wild-type mammary glands taken from a parous host. Scale bar in (b) denotes 500 m and applies to all whole mounts. Adapted from Lydon et al. [5].

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