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Table 4 Genotype distributions of V89L and TA repeat polymorphisms

From: A49T, V89L and TA repeat polymorphisms of steroid 5α-reductase type II and breast cancer risk in Japanese women

 

V89L genotype (%)

 

Fisher's exact

TA genotype

V/V

V/L

L/L

Total

P value

Cases

     

   TA(0/0)

39 (16.6)

88 (37.4)

51 (21.7)

178 (75.7)

 

   TA(0/9)

19 (8.1)

35 (14.9)

0 (0.0)

54 (23.0)

 

   TA(9/9)

3 (1.3)

0 (0.0)

0 (0.0)

3 (1.3)

 

   Total

61 (26.0)

123 (52.3)

51 (21.7)

235 (100.0)

< 0.001

Controls

     

   TA(0/0)

21 (11.5)

57 (31.2)

60 (32.8)

138 (75.4)

 

   TA(0/9)

19 (10.4)

22 (12.0)

0 (0.0)

41 (22.4)

 

   TA(9/9)

4 (2.2)

0 (0.0)

0 (0.0)

4 (2.2)

 

   Total

44 (24.0)

79 (43.2)

60 (32.8)

183 (100.0)

< 0.001

  1. Percentages are shown in parentheses.