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Table 1 Mean percentage of breast density by descriptive characteristics (n = 396)

From: Genetic determinants of mammographic density

Characteristic

n (%)

Mean % density

P §

Race*

   African-American

152 (38)

34.8

 

   Whites

244 (68)

34.8

0.98

Menopausal status/ HRT use**,†

   Premenopausal

176 (44)

35.4

 

   Postmenopausal

   

Never used or past user of HRT

67 (17)

30.4

 

Current user of ERT

53 (13)

39.3

 

Current user of EPRT

51 (13)

39.8

0.08

Age at mammogram (years)

   ≤ 40

91 (23)

45.6

 

   41–45

84 (21)

41.2

 

   46–50

41 (10)

38.3

 

   51–55

74 (19)

34.4

 

   56–60

69 (17)

28.3

 

   >60

37 (9)

28.9

<0.0001

Body mass index (kg/m2)**

   <22

114 (29)

49.8

 

   22–24.9

107 (27)

38.3

 

   25–29.9

111 (28)

29.2

 

   ≥ 30

64 (16)

21.8

<0.0001

Parity**

   0

83 (21)

45.1

 

   1–2

175 (44)

38.0

 

   3+

138 (35)

29.1

<0.0001

Age at first birth (years)**

   <25

191(61)

30.9

 

   25–30

69 (22)

35.1

 

   ≥ 30

53 (17)

43.8

0.0004

Age at menarche (years)**

   <12

106 (27)

32.6

 

   12

105 (27)

36.5

 

   13

97 (24)

34.7

 

   >13

88 (22)

41.3

0.04

First-degree family history of breast cancer**,‡

   No

256 (65)

35.0

 

   Yes

120 (30)

39.3

0.12

  1. *Adjusted for age and body mass index. **Adjusted for age. † n = 49 missing menopausal/ hormone replacement therapy (HRT) status. ‡ n = 20 missing family history information. §Analysis of covariance. EPRT, estrogen plus progestin replacement therapy; ERT, estrogen replacement therapy.