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Table 2 PIK3CA mutation-dependent responsiveness to pertuzumab treatment (all arms pooled)

From: Evaluating the predictive value of biomarkers for efficacy outcomes in response to pertuzumab- and trastuzumab-based therapy: an exploratory analysis of the TRYPHAENA study

PIK3CA exons

Number of patients achieving a pathological complete response (pCR) per-exon mutation/total number of patients with a mutation in that exon (population pCR rate 139/225 (62%))

Exon 7

0/0

Exon 9

5/11

Exon 20

14/28