Skip to main content

Table 3 Relationship between Ki67 and phosphatidylinositol 3-kinase pathway gene signatures a

From: Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition

  

With PAGs

Without PAGs

  

PIK3CA-GS (Loi)

PI3K-GS (Creighton)

PTEN-loss-GS (Saal)

PIK3CA-noPAG-GS (Loi)

PI3K-noPAG-GS (Creighton)

PTEN-loss-noPAG-GS (Saal)

 

n

Spearman’s r

P-value

Spearman’s r

P-value

Spearman’s r

P-value

Spearman’s r

P-value

Spearman’s r

P-value

Spearman’s r

P-value

Baseline Ki67

64

-0.101

0.427

0.371

0.003

0.508

<0.0001

-0.082

0.518

0.370

0.003

0.347

0.005

2-week Ki67

57

0.084

0.534

0.188

0.162

0.219

0.102

0.120

0.374

0.186

0.167

0.132

0.329

2-wk/pre-Ki67%

56

0.212

0.117

0.036

0.792

-0.004

0.976

0.246

0.068

0.033

0.811

-0.017

0.901

  1. aGS, Gene signature; PAG, Proliferation-associated gene.
Back to article page

Breast Cancer Research

ISSN: 1465-542X

Contact us