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Figure 2 | Breast Cancer Research

Figure 2

From: Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells

Figure 2

Synergistic effect of lestaurtinib in combination with AG14361 in vitro . Synergistic effect of lestaurtinib in the presence of IC50 AG14361 on 92 J isogenic cell lines (A), MDA-MB-231 isogenic cell lines (B), and 69 and Ras cell lines (C) revealed by ATP release assay. Data shown represent mean ± standard deviation (SD) from triplicate experiments. IC50, 50% inhibition dose.

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