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Figure 2 | Breast Cancer Research

Figure 2

From: Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity

Figure 2

Kaplan-Meier analysis of H4K20me3 and H3K9me3 levels in breast cancer patients. The three-point scoring system used in FigureĀ 1 was consolidated into a two-point scale. Cases with scores of 0 and 1 constitute the low-staining group, and cases with a score of 2 constitute the high-staining group. Then patient overall survival time (A and C) and disease-free survival rate (B and D) were compared between the H4K20me3 low- and high-staining groups (A and B), and between the H3K9me3 low- and high-staining groups (C and D), by Kaplan-Meier analysis. This method yields a survival curve that considers both outcomes (death) and censored cases. Significance is calculated by log-rank test between two groups (low- and high-staining).

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