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Table 3 Multiple linear regression analysis of the association between five putative biomarker proteins and their combined value with clinical pathologic features

From: Novel serum protein biomarker panel revealed by mass spectrometry and its prognostic value in breast cancer

Tumor variables Pvalue
ApoCI C3a-desArg Transthyretin ApoAI ApoH fragment Combined parameter
Grade (G1, n = 22; G2, n = 64; G3, n = 96) 0.781 0.908 0.862 0.876 0.836 0.697
Tumor size (T ≤2 cm; T >2 cm) 0.314 0.867 0.004 0.921 0.516 0.018
LN (positive, n = 79; negative, n = 78) 0.182 0.503 0.397 0.119 0.499 0.016
ER (positive, n = 131; negative, n = 50) 0.550 0.756 0.151 0.517 0.124 0.341
PR (positive, n = 121; negative, n = 63) 0.723 0.774 0.010 0.171 0.340 0.825
HER2 (positive, n = 38; negative, n = 133) 0.509 0.280 0.968 0.018 0.733 0.087
  1. ApoCI/AI/H, apolipoprotein CI/AI/H; C3a-desArg, C3a des-arginine anaphylatoxin; LN, lymph node involvement; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.