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Table 3 Multiple linear regression analysis of the association between five putative biomarker proteins and their combined value with clinical pathologic features

From: Novel serum protein biomarker panel revealed by mass spectrometry and its prognostic value in breast cancer

Tumor variables

Pvalue

ApoCI

C3a-desArg

Transthyretin

ApoAI

ApoH fragment

Combined parameter

Grade (G1, n = 22; G2, n = 64; G3, n = 96)

0.781

0.908

0.862

0.876

0.836

0.697

Tumor size (T ≤2 cm; T >2 cm)

0.314

0.867

0.004

0.921

0.516

0.018

LN (positive, n = 79; negative, n = 78)

0.182

0.503

0.397

0.119

0.499

0.016

ER (positive, n = 131; negative, n = 50)

0.550

0.756

0.151

0.517

0.124

0.341

PR (positive, n = 121; negative, n = 63)

0.723

0.774

0.010

0.171

0.340

0.825

HER2 (positive, n = 38; negative, n = 133)

0.509

0.280

0.968

0.018

0.733

0.087

  1. ApoCI/AI/H, apolipoprotein CI/AI/H; C3a-desArg, C3a des-arginine anaphylatoxin; LN, lymph node involvement; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.