Figure 2

Relative abundance of the serum proteins used to develop the five-protein parameter. Significantly different peak intensities observed between breast cancer patient (BC) and healthy volunteer (HV) samples on the combined training and validation sets: (A) m/z 3808 on CM10 weak cation-exchange surface; (B) m/z 6624 on H50 hydrophobic surface; (C) m/z 8916 on Q10 strong anion exchange surface; (D) m/z 13870 on IMAC30 immobilized metal affinity surface; (E) m/z 28268 on Q10 strong anion exchange surface. Data were analyzed by the Mann-Whitney U test.