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Table 1 Distribution of cases and controls by age, race or ethnicity, and study center †

From: Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study

Distributions

Cases, n (%)

Controls, n (%)

Age range, yr

 

  ≤30

108 (8.2%)

67 (6.0%)

  31-35

325 (24.8%)

172 (15.3%)

  36-40

436 (33.2%)

237 (21.1%)

  41-45

443 (33.8%)

203 (18.1%)

  46-50

0 (0.0%)

230 (20.5%)

  51-55

0 (0.0%)

212 (18.9%)

Total

1,312 (100.0%)

1,121 (100.0%)

Race or ethnicity

 

  Caucasian

848 (64.6%)

967 (86.3%)

  East Asian

208 (15.9%)

71 (6.3%)

  Latina

158 (12.0%)

47 (4.2%)

  Recent African Ancestry

98 (7.5%)

36 (3.2%)

Total

1,312 (100.0%)

1,121 (100.0%)

Study center

 

  BCFR-Australia

593 (45.2%)

522 (46.6%)

  BCFR-Canada

302 (23.0%)

463 (41.3%)

  BCFR-Northern California

417 (31.8%)

136 (12.1%)

Total

1,312 (100.0%)

1,121 (100.0%)

  1. †The three subjects excluded because of poor mutation-screening performance are not included; percentage data are the percentages of the total number of patient or control DNA in the category indicated that met the mutation-screening quality control criterion; BCFR, Breast Cancer Family Registry.