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Figure 1 | Breast Cancer Research

Figure 1

From: Rare key functional domain missense substitutions in MRE11A, RAD50, and NBNcontribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study

Figure 1

MRE11, RAD50, and nibrin key functional domains. The protein domain diagrams are updated from Williams et al. [4] and include information from the InterPro protein sequence analysis and classification database, the Uniprot Protein Knowledgebase, and the NCBI Conserved Domains Database [4750] plus structural studies of the MRN proteins [5163].

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