JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI

Breast Cancer Research

Table 1 Association between JMJD2A expression and disease parameters in 155 cases of breast cancer

	Total	JMJD2A				P-value	Correlation coefficient
		0 (−)	1 (+)	2 (++)	3 (+++)
		n = 11	n = 56	n = 53	n = 35
TNM¹ stage
I and II	139	10	54	49	26	0.004**	0.227
III and IV	16	1	2	4	9	0.004**	0.227
Tumor size
≤2 cm	110	6	48	37	19	0.026*	0.179
2 cm < T ≤5 cm	42	5	7	14	16
>5 cm	3	0	1	2	0
Lymph node metastasis
Negative	100	9	29	35	27	0.102	−0.132
Positive	55	2	27	18	8	0.102	−0.132
Age
<50 years	46	4	21	13	8	0.092	0.136
≥50 years	109	7	35	40	27	0.092	0.136

¹TNM stage is a classification of malignant tumors used by the International Federation of Gynecology and Obstetrics (FIGO). T describes the size of primary tumor, N describes nearby lymph nodes that are involved, and M describes distant metastasis. *P <0.05, **P <0.01.

ISSN: 1465-542X