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Figure 1 | Breast Cancer Research

Figure 1

From: Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Figure 1

Association of rs10235235 with breast cancer risk for women of European ancestry. Forest plots of the association of the rs10235235 AG (heterozygote) genotype (A) and GG (homozygote) genotype (B) with breast cancer risk for women of European ancestry. Horizontal lines, 95% confidence intervals (CIs); square boxes, study-specific fixed-effects estimates; diamond, combined, fixed-effects estimate of the odds ratio (OR) and 95% CI. Vertical line, null effect (OR = 1.0); dashed vertical line, estimated heterozygote OR (A) and estimated homozygote OR (B). Homozygote ORs for six studies (CTS, DEMOKRITOS, kConFab/AOCS, NBCS, NBHS and RPCI) could not be estimated because there were no GG homozygotes among cases or among controls in each of these studies (see Table S2 in Additional file 1).

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