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Table 1 Multivariate analysis of factors associated with recurrence free survival (RFS)

From: The mechanistic target for rapamycin pathway is related to the phosphorylation score for estrogen receptor-α in human breast tumors in vivo

Single predictor Number Hazard ratio 95% CI on HR P
Age 50+ versus <50 420 1.57 0.80 to 3.07 0.19
Tumor >2.5 cm 422 1.85 1.36 to 2.51 <.0001
Node Pos versus Neg 415 2.02 1.48 to 2.76 <.0001
Grade (Low, Mid High) 420 1.45 1.12 to 1.88 0.0055
PR_LBA >20 421 0.6 0.44 to 0.81 0.0010
P7 Score High 340 2.23 1.37 to 3.61 0.0012
pmTor >80 337 0.58 0.41 to 0.83 0.0032
mTor >180 329 0.73 0.51 to 1.04 0.084
Multi predictor     
Age 50+ versus <50 277 1.34 0.53 to 3.36 0.54
Tumor >2.5 cm   1.77 1.20 to 2.61 0.0041
Node Pos versus Neg   1.61 1.07 to 2.43 0.022
Grade (Low, Mid High)   1.21 0.88 to 1.64 0.24
PR_LBA >20   0.61 0.42 to 0.89 0.011
P7 Score High   1.77 0.99 to 3.18 0.054
pmTor >80   0.80 0.54 to 1.20 0.28
  1. CI, confidence interval; mTOR, mechanistic target of rapamycin; PR_LBA, Progesterone Receptor Ligand Binding Assay.