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Table 1 Multivariate analysis of factors associated with recurrence free survival (RFS)

From: The mechanistic target for rapamycin pathway is related to the phosphorylation score for estrogen receptor-α in human breast tumors in vivo

Single predictor

Number

Hazard ratio

95% CI on HR

P

Age 50+ versus <50

420

1.57

0.80 to 3.07

0.19

Tumor >2.5 cm

422

1.85

1.36 to 2.51

<.0001

Node Pos versus Neg

415

2.02

1.48 to 2.76

<.0001

Grade (Low, Mid High)

420

1.45

1.12 to 1.88

0.0055

PR_LBA >20

421

0.6

0.44 to 0.81

0.0010

P7 Score High

340

2.23

1.37 to 3.61

0.0012

pmTor >80

337

0.58

0.41 to 0.83

0.0032

mTor >180

329

0.73

0.51 to 1.04

0.084

Multi predictor

    

Age 50+ versus <50

277

1.34

0.53 to 3.36

0.54

Tumor >2.5 cm

 

1.77

1.20 to 2.61

0.0041

Node Pos versus Neg

 

1.61

1.07 to 2.43

0.022

Grade (Low, Mid High)

 

1.21

0.88 to 1.64

0.24

PR_LBA >20

 

0.61

0.42 to 0.89

0.011

P7 Score High

 

1.77

0.99 to 3.18

0.054

pmTor >80

 

0.80

0.54 to 1.20

0.28

  1. CI, confidence interval; mTOR, mechanistic target of rapamycin; PR_LBA, Progesterone Receptor Ligand Binding Assay.
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Breast Cancer Research

ISSN: 1465-542X

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