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Table 2 Agreement (%) between academic readers and Veridex consensus (VC)

From: International study on inter-reader variability for circulating tumor cells in breast cancer

  No CTC versus CTC    CTC HER2- versus CTC HER2+  
RDs N Agreement (%) Kappa statistic Kappa agreement N Agreement (%) Kappa statistic Kappa agreement
A 267 91.8% 0.83 Almost perfect 155 81.3% 0.63 Substantial
B 267 91.4% 0.82 Almost perfect 155 81.3% 0.63 Substantial
C 267 92.5% 0.84 Almost perfect 155 90.3% 0.81 Almost perfect
D 267 91.8% 0.83 Almost perfect 155 71.6% 0.47 Moderate
E 266 95.1% 0.90 Almost perfect 154 93.5% 0.87 Almost perfect
F 267 92.1% 0.84 Almost perfect 155 87.1% 0.75 Substantial
G 267 91.4% 0.82 Almost perfect 155 91.0% 0.82 Almost perfect
H 267 91.4% 0.82 Almost perfect 155 88.4% 0.78 Substantial
I 267 92.1% 0.84 Almost perfect 155 91.6% 0.84 Almost perfect
J 267 83.9% 0.65 Substantial 155 76.8% 0.55 Moderate
K 220 87.3% 0.74 Substantial 117 79.5% 0.59 Moderate
L 266 92.9% 0.85 Almost perfect 154 94.8% 0.90 Almost perfect
M 220 87.3% 0.74 Substantial 117 90.6% 0.82 Almost perfect
N 267 95.9% 0.92 Almost perfect 155 92.3% 0.85 Almost perfect
O 267 96.6% 0.93 Almost perfect 155 92.9% 0.86 Almost perfect
P 267 94.4% 0.88 Almost perfect 155 85.2% 0.72 Substantial
Q 218 91.7% 0.83 Almost perfect 113 84.1% 0.69 Substantial
R 218 91.7% 0.83 Almost perfect 113 85.8% 0.73 Substantial
S 220 92.7% 0.85 Almost perfect 117 86.3% 0.73 Substantial
T 266 69.2% 0.37 Fair 154 51.3% 0.25 Fair
U 267 91.4% 0.82 Almost perfect 155 91.0% 0.82 Almost perfect
V 220 91.8% 0.84 Almost perfect 117 82.1% 0.66 Substantial
  1. CTC, circulating tumor cell; RDs, readers; N, number of images. Kappa Agreement, below 0.00 Poor; 0.00 to 0.20 Slight; 0.21 to 0.40 Fair; 0.41 to 0.60 Moderate; 0.61 to 0.80 Substantial; 0.81 to 1.00 Almost Perfect.