From: International study on inter-reader variability for circulating tumor cells in breast cancer
Patients, number (%) | CellSearch® images, number (%) | |
---|---|---|
n = 131 (100%) | n = 272 (100%) | |
Dataset | ||
Institute Jules Bordet | 34 (26) | 60 (22) |
Institute Curie | 60 (46) | 114 (42) |
University of Hamburg | 37 (28) | 98 (36) |
Age, years | ||
≤50 | 58 (44) | 108 (40) |
>50 | 66 (51) | 147 (54) |
Unknown | 7 (5) | 17 (6) |
ER | ||
Negative | 54 (41) | 106 (39) |
Positive | 68 (52) | 139 (51) |
Unknown | 9 (7) | 27 (10) |
HER2 | ||
Negative | 103 (79) | 193 (71) |
Positive | 15 (11) | 44 (16) |
Unknown | 13 (10) | 35 (13) |
Histology grade | ||
1 | 5 (4) | 6 (2) |
2 | 46 (35) | 85 (31) |
3 | 69 (53) | 147 (54) |
Unknown | 11 (8) | 34 (13) |
Histology | ||
Ductal | 99 (76) | 202 (74) |
Lobular | 10 (8) | 12 (4) |
Other | 7 (5) | 18 (7) |
Unknown | 15 (11) | 40 (15) |
Stage | ||
M0 | 109 (83) | 215 (79) |
M1 | 22 (17) | 57 (21) |
CTC count 1 | ||
<5 CTCs | 90 (69) | 150 (55) |
≥5 CTCs | 40 (30) | 120 (44) |
Unknown | 2 (1) | 2 (1) |
Systemic therapy before blood sample collection 2 | ||
No | 87 (65) | 168 (62) |
Yes | 31 (24) | 62 (23) |
Unknown | 15 (11) | 42 (15) |