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Table 1 CellSearch® images and patient characteristics

From: International study on inter-reader variability for circulating tumor cells in breast cancer

 

Patients, number (%)

CellSearch® images, number (%)

 

n = 131 (100%)

n = 272 (100%)

Dataset

  

  Institute Jules Bordet

34 (26)

60 (22)

  Institute Curie

60 (46)

114 (42)

  University of Hamburg

37 (28)

98 (36)

Age, years

  

  ≤50

58 (44)

108 (40)

  >50

66 (51)

147 (54)

  Unknown

7 (5)

17 (6)

ER

  

  Negative

54 (41)

106 (39)

  Positive

68 (52)

139 (51)

  Unknown

9 (7)

27 (10)

HER2

  

  Negative

103 (79)

193 (71)

  Positive

15 (11)

44 (16)

  Unknown

13 (10)

35 (13)

Histology grade

  

  1

5 (4)

6 (2)

  2

46 (35)

85 (31)

  3

69 (53)

147 (54)

  Unknown

11 (8)

34 (13)

Histology

  

  Ductal

99 (76)

202 (74)

  Lobular

10 (8)

12 (4)

  Other

7 (5)

18 (7)

  Unknown

15 (11)

40 (15)

Stage

  

  M0

109 (83)

215 (79)

  M1

22 (17)

57 (21)

CTC count 1

  

  <5 CTCs

90 (69)

150 (55)

  ≥5 CTCs

40 (30)

120 (44)

  Unknown

2 (1)

2 (1)

Systemic therapy before blood sample collection 2

  

  No

87 (65)

168 (62)

  Yes

31 (24)

62 (23)

  Unknown

15 (11)

42 (15)

  1. 1One patient with two samples (<5 CTCs and ≥ 5CTCs) was included; 2two patients with samples before and after treatment were included. ER, estrogen receptor; CTC, circulating tumor cell; M0, non-metastatic; M1, metastatic.