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Table 1 Characteristics of women with invasive breast cancer according to smoking status at diagnosis (1987 to 2008)

From: Smoking at time of diagnosis and breast cancer-specific survival: new findings and systematic review with meta-analysis

 

Smoking status at time of diagnosis

 

Current (n = 1,079)

Former (n = 1,303)

Never (n = 3,510)

Total (n = 5,892)

Characteristics of women

Age (years), mean (SD)

52.8 (11.5)

56.1 (11.3)

59.3 (13.1)

57.4 (12.7)

Body mass indexb (kg/m2), mean (SD)

24.0 (4.6)

25.5 (5.0)

25.1 (4.7)

25.0 (4.8)

Age (years) at menarcheb, mean (SD)

12.8 (1.8)

12.8 (1.7)

12.9 (1.6)

12.9 (1.7)

Parityb, mean (SD)

1.9 (1.8)

1.9 (1.8)

2.3 (2.2)

2.1 (2.1)

Postmenopausal womenb (%)

60.5

67.6

73.6

69.8

Age (years) at menopauseb, mean (SD)

45.4 (6.9)

46.3 (6.8)

47.1 (6.4)

46.7 (6.6)

Hormone replacement therapy current useb (%)

17.1

17.2

17.5

17.3

Family history of breast cancera, b (%)

23.2

24.5

25.6

24.9

Diabetesb (%)

1.9

1.9

2.6

2.3

Current alcohol intakeb (%)

39.5

47.3

27.3

34.2

Characteristics of the disease and treatment

Tumor size (mm)b, mean (SD)

22.9 (17.7)

22.7 (17.5)

23.3 (18.3)

23.1 (18.0)

Number of axillary nodes examinedb, c, mean (SD)

12.4 (7.8)

11.1 (8.2)

11.2 (7.7)

11.4 (7.9)

Positive estrogen receptors (%)

73.3

77.7

73.4

74.1

Positive progesterone receptors (%)

56.1

56.9

52.2

53.6

Well differentiated histological gradeb (%)

24.5

27.8

26.0

26.1

Regional involvement (%)

39.4

36.4

36.1

36.8

Distant metastasis at diagnosis (%)

3.2

2.5

3.2

3.0

Breast-conserving surgeryd (%)

68.3

72.1

67.4

68.6

Axillary surgeryd (%)

89.4

90.9

85.0

87.1

Neoadjuvant therapyd (%)

5.4

6.7

6.4

6.3

Adjuvant radiotherapyb, d (%)

75.9

79.8

71.4

74.1

Adjuvant chemotherapyb, d (%)

49.0

48.6

41.4

44.4

Adjuvant endocrine therapyb, d (%)

60.8

65.2

64.7

64.1

  1. aMother, sister and daughter. bMissing information in less than 5% of women, except for histological grade (14%), pathological tumor size (6.1%), and alcohol use (47.4%). cIn 5,132 women who had an axillary surgery or a sentinel node biopsy. dIn 5,713 women with nonmetastatic breast cancer.