Smoking status at time of diagnosis | ||||
---|---|---|---|---|
Current (n = 1,079) | Former (n = 1,303) | Never (n = 3,510) | Total (n = 5,892) | |
Characteristics of women | ||||
Age (years), mean (SD) | 52.8 (11.5) | 56.1 (11.3) | 59.3 (13.1) | 57.4 (12.7) |
Body mass indexb (kg/m2), mean (SD) | 24.0 (4.6) | 25.5 (5.0) | 25.1 (4.7) | 25.0 (4.8) |
Age (years) at menarcheb, mean (SD) | 12.8 (1.8) | 12.8 (1.7) | 12.9 (1.6) | 12.9 (1.7) |
Parityb, mean (SD) | 1.9 (1.8) | 1.9 (1.8) | 2.3 (2.2) | 2.1 (2.1) |
Postmenopausal womenb (%) | 60.5 | 67.6 | 73.6 | 69.8 |
Age (years) at menopauseb, mean (SD) | 45.4 (6.9) | 46.3 (6.8) | 47.1 (6.4) | 46.7 (6.6) |
Hormone replacement therapy current useb (%) | 17.1 | 17.2 | 17.5 | 17.3 |
Family history of breast cancera, b (%) | 23.2 | 24.5 | 25.6 | 24.9 |
Diabetesb (%) | 1.9 | 1.9 | 2.6 | 2.3 |
Current alcohol intakeb (%) | 39.5 | 47.3 | 27.3 | 34.2 |
Characteristics of the disease and treatment | ||||
Tumor size (mm)b, mean (SD) | 22.9 (17.7) | 22.7 (17.5) | 23.3 (18.3) | 23.1 (18.0) |
Number of axillary nodes examinedb, c, mean (SD) | 12.4 (7.8) | 11.1 (8.2) | 11.2 (7.7) | 11.4 (7.9) |
Positive estrogen receptors (%) | 73.3 | 77.7 | 73.4 | 74.1 |
Positive progesterone receptors (%) | 56.1 | 56.9 | 52.2 | 53.6 |
Well differentiated histological gradeb (%) | 24.5 | 27.8 | 26.0 | 26.1 |
Regional involvement (%) | 39.4 | 36.4 | 36.1 | 36.8 |
Distant metastasis at diagnosis (%) | 3.2 | 2.5 | 3.2 | 3.0 |
Breast-conserving surgeryd (%) | 68.3 | 72.1 | 67.4 | 68.6 |
Axillary surgeryd (%) | 89.4 | 90.9 | 85.0 | 87.1 |
Neoadjuvant therapyd (%) | 5.4 | 6.7 | 6.4 | 6.3 |
Adjuvant radiotherapyb, d (%) | 75.9 | 79.8 | 71.4 | 74.1 |
Adjuvant chemotherapyb, d (%) | 49.0 | 48.6 | 41.4 | 44.4 |
Adjuvant endocrine therapyb, d (%) | 60.8 | 65.2 | 64.7 | 64.1 |