Skip to main content
Figure 6 | Breast Cancer Research

Figure 6

From: Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition

Figure 6

Protein expression and phosphorylation of PTEN, mTOR, S6K1, 4EBP1, and eIF4E in xenografts. Western blot images were cropped at the molecular weight of each of the target proteins. Pretreatment samples were collected prior to initiation of treatment; control samples (vehicle control), rapamycin-treated and CCI-779-treated samples were collected at the end of the treatment period. Tubulin was used as a loading control. See also Table S5 in Additional file 7. CCI-779, temsirolimus.

Back to article page