Table 1 Characteristics of breast cancer patients who died from breast cancer (cases) compared with controls
Cancer-specific deaths n (%) | Controls n (%) | P-value | |
|---|---|---|---|
(n = 1,435) | (n = 5,697) | ||
Year of cancer diagnosis | |||
1998 to 2000 | 500 (34.8%) | 1,979 (34.7%) | Matched |
2001 to 2003 | 518 (36.1%) | 2,060 (36.2%) | |
2003 to 2006 | 417 (29.1%) | 1,658 (29.1%) | |
Age at cancer diagnosis | |||
<40 | 92 (6.4%) | 352 (6.2%) | Matched |
40 to 49 | 247 (17.2%) | 985 (17.3%) | |
50 to 59 | 286 (19.9%) | 1,144 (20.1%) | |
60 to 69 | 273 (19.0%) | 1,092 (19.2%) | |
70 to 79 | 318 (22.2%) | 1,271 (22.3%) | |
80 to 89 | 181 (12.6%) | 722 (12.7%) | |
≥90 | 38 (2.7%) | 131 (2.3%) | Matched |
Follow-up time (years): mean (sd) | 3.9 (2.3) | 3.9 (2.3) | |
range | 1.0 to 12.8 | 1.0 to 12.8 | |
Grade | |||
Well | 54 (5.9) | 751 (19.4) | <0.001 |
Poor | 377 (40.9) | 1,900 (49.1) | |
Moderate | 492 (53.3) | 1,217 (31.5) | |
Missing | 512 | 1,829 | |
Stage | |||
1 | 72 (11.0%) | 1,133 (41.8%) | <0.001 |
2 | 402 (61.5%) | 1,379 (50.8%) | |
3 | 116 (17.7%) | 167 (6.2%) | |
4 | 64 (9.8%) | 35 (1.3%) | |
Missing | 781 | 2,983 | |
Treatment within six months of cancer diagnosis | |||
Surgery | 1,087 (75.8%) | 4,842 (85.0%) | <0.001 |
Chemotherapy | 573 (39.9%) | 1,344 (23.6%) | <0.001 |
Radiotherapy | 2,703 (47.5%) | 700 (48.8%) | 0.31 |
Smoking prior to cancer diagnosis | |||
Non-smoker | 710 (59.9%) | 3,037 (64.0%) | 0.03 |
Ex-smoker | 226 (19.1%) | 832 (17.5%) | |
Current smoker | 249 (21.0%) | 874 (18.4%) | |
Missing | 250 | 954 | |
Alcohol prior to cancer diagnosis | |||
Never consumed alcohol | 203 (19.6) | 806 (19.2) | 0.94 |
Alcohol consumer | 831 (80.4) | 3,399 (80.8) | |
Missing | 401 | 1,492 | |
BMI (kg/m2) prior to cancer diagnosis: | 1,049 | 4,333 | |
Mean (SD) | 26.6 (5.4) | 26.3 (5.1) | 0.04 |
Comorbidity prior to cancer diagnosis | |||
Cerebrovascular disease | 67 (4.7) | 219 (3.8) | 0.15 |
Chronic pulmonary disease | 249 (17.4) | 906 (15.9) | 0.18 |
Congestive heart disease | 38 (2.7) | 140 (2.5) | 0.72 |
Diabetes | 81 (5.6) | 274 (4.8) | 0.18 |
Myocardial infarction | 20 (1.4) | 79 (1.4) | 0.97 |
Peptic ulcer disease | 35 (2.4) | 145 (2.6) | 0.81 |
Peripheral vascular disease | 35 (2.4) | 73 (1.3) | 0.001 |
Rheumatological disease | 62 (4.3) | 187 (3.3) | 0.07 |