Skip to main content

Table 1 Characteristics of breast cancer patients who died from breast cancer (cases) compared with controls

From: Post-diagnostic prescriptions for low-dose aspirin and breast cancer-specific survival: a nested case-control study in a breast cancer cohort from the UK Clinical Practice Research Datalink

  Cancer-specific deaths n (%) Controls n (%) P-value
  (n = 1,435) (n = 5,697)  
Year of cancer diagnosis    
  1998 to 2000 500 (34.8%) 1,979 (34.7%) Matched
  2001 to 2003 518 (36.1%) 2,060 (36.2%)  
  2003 to 2006 417 (29.1%) 1,658 (29.1%)  
Age at cancer diagnosis    
  <40 92 (6.4%) 352 (6.2%) Matched
  40 to 49 247 (17.2%) 985 (17.3%)  
  50 to 59 286 (19.9%) 1,144 (20.1%)  
  60 to 69 273 (19.0%) 1,092 (19.2%)  
  70 to 79 318 (22.2%) 1,271 (22.3%)  
  80 to 89 181 (12.6%) 722 (12.7%)  
  ≥90 38 (2.7%) 131 (2.3%) Matched
Follow-up time (years): mean (sd) 3.9 (2.3) 3.9 (2.3)  
   range 1.0 to 12.8 1.0 to 12.8  
Grade    
  Well 54 (5.9) 751 (19.4) <0.001
  Poor 377 (40.9) 1,900 (49.1)  
  Moderate 492 (53.3) 1,217 (31.5)  
  Missing 512 1,829  
Stage    
  1 72 (11.0%) 1,133 (41.8%) <0.001
  2 402 (61.5%) 1,379 (50.8%)  
  3 116 (17.7%) 167 (6.2%)  
  4 64 (9.8%) 35 (1.3%)  
  Missing 781 2,983  
Treatment within six months of cancer diagnosis   
  Surgery 1,087 (75.8%) 4,842 (85.0%) <0.001
  Chemotherapy 573 (39.9%) 1,344 (23.6%) <0.001
  Radiotherapy 2,703 (47.5%) 700 (48.8%) 0.31
Smoking prior to cancer diagnosis    
  Non-smoker 710 (59.9%) 3,037 (64.0%) 0.03
  Ex-smoker 226 (19.1%) 832 (17.5%)  
  Current smoker 249 (21.0%) 874 (18.4%)  
  Missing 250 954  
Alcohol prior to cancer diagnosis    
  Never consumed alcohol 203 (19.6) 806 (19.2) 0.94
  Alcohol consumer 831 (80.4) 3,399 (80.8)  
  Missing 401 1,492  
BMI (kg/m2) prior to cancer diagnosis: 1,049 4,333  
  Mean (SD) 26.6 (5.4) 26.3 (5.1) 0.04
Comorbidity prior to cancer diagnosis   
Cerebrovascular disease 67 (4.7) 219 (3.8) 0.15
Chronic pulmonary disease 249 (17.4) 906 (15.9) 0.18
Congestive heart disease 38 (2.7) 140 (2.5) 0.72
Diabetes 81 (5.6) 274 (4.8) 0.18
Myocardial infarction 20 (1.4) 79 (1.4) 0.97
Peptic ulcer disease 35 (2.4) 145 (2.6) 0.81
Peripheral vascular disease 35 (2.4) 73 (1.3) 0.001
Rheumatological disease 62 (4.3) 187 (3.3) 0.07