Figure 8

Chemical inhibition of RIP2 leads to decreased JNK and FAK activation. (A) Western blots showing relative expressions of various proteins in MDA-MB-231 cells treated with indicated doses of PP2. (B) Representative Matrigelâ„¢ invasion assays from MDA-MB-231 cells at 16 hours when treated with indicated doses of PP2. (C) Quantification of Matrigelâ„¢ invasion assay results for MDA-MB-231 cells treated with PP2 with error bars representing standard error of the mean (SEM). Columns represent results from two separate experiments done in triplicates. Statistics per Student t-test.