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Table 1 Statistical results of NDRG2 expression in 269 breast cancer specimens

From: N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma

Variables

N

NDRG2 expression

 
  

Low expression, n(%)

High expression, n(%)

P-value

Age (years)

   

0.104b

  ≤50

112

72 (64.3)

40 (35.7)

 

  >50

157

85 (54.1)

72 (45.9)

 

Tumour size

   

0.536b

  ≤2 cm

121

68 (56.2)

53 (43.8)

 

  >2 cm

148

89 (60.1)

59 (39.9)

 

TNM stage

   

<0.0001b

  I to II

114

48 (42.1)

66 (57.9)

 

  III to IV

155

109 (70.3)

46 (29.7)

 

Lymph node metastasis

   

0.009b

  Negative

114

56 (49.1)

58 (50.9)

 

  Positive

155

101 (65.2)

54 (34.8)

 

Histology

   

<0.0001c

  Poorly differentiated

103

75 (72.8)

28 (27.2)

 

  Moderately differentiated

83

52 (62.7)

31 (37.3)

 

  Well differentiated

83

30 (36.1)

53 (63.9)

 

Tumour invasion

   

0.387b

  No

134

82 (61.2)

52 (38.8)

 

  Yes

135

75 (55.6)

60 (44.4)

 

ER status

   

0.010b

  Negative

79

56 (70.9)

23 (29.1)

 

  Positive

190

101 (53.2)

89 (46.8)

 

Her-2 status

   

0.010b

  Negative

201

108 (53.7)

93 (46.3)

 

  Positive

68

49 (72.1)

19 (27.9)

 

Ki67 status

   

0.006b

  Negative

119

58 (48.7)

61 (51.3)

 

  Positive

150

99 (66.0)

51 (34.0)

 
  1. aER, Oestrogen receptor; Her-2, Human epidermal growth factor receptor 2; NDRG2, N-myc downstream-regulated gene 2; TNM, tumour, node, metastasis. bFisher’s exact test was used for statistical analyses. P < 0.05 were considered statistically significant. cPearson’s χ2 test was used for statistical analyses.
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Breast Cancer Research

ISSN: 1465-542X

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