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Table 3 Cell cycle phase and function

From: Next-generation transcriptome sequencing of the premenopausal breast epithelium using specimens from a normal human breast tissue bank

  G1/S S G2 G2/M M/G1
DNA replication initiation CDC45L     MCM10
CDC6
MCM2
MCM4
ORC1
ORC6
CDT1
Nucleotide metabolism     DTYMK  
RRM2
DNA replication and repair BRIP1 TYMS TOP2A FANCA  
BLM RAD54L
DNA2 NEIL3
RAD51 PTTG1
EXO1 POLQ
POLE2 TRIP13
PCNA KIAA0101
UNG
BRCA1
GINS2
DTL
Chromatin assembly and disassembly HELLS HIST1H1B HJURP ASF1B  
EZH2 HIST1H1D
  HIST1H2AB
HIST1H2AH, HIST1H2AK, HIST1H2AM, HIST1H2AG,
HIST1H2AL
HIST1H2AJ
HIST1H2BH
HIST1H2BF, HIST1H2BE
HIST1H2BL
HIST1H2BM
HIST1H2BN
HIST1H2BO
HIST1H2AD, HIST1H3C, HIST1H3F, HIST1H3G, HIST1H3B, HIST1H3H, HIST1H3J, HIST1H3A, HIST1H3D
HIST1H4L, HIST1H4F, HIST1H4A
Cell cycle regulation-interphase CLSPN    CCNA2  
E2F1 CKS2
CHEK1 MKI67
Cell cycle regulation-mitosis FBXO5    FOXM1 CCNB1
CCNB2  
CDC20
CDC25C
CIT
MELK
PKMYT1  
UBE2C
Microtubules and spindle formation     KIF11 KIF18A
KIF14 KIF4A
KIF15
KIF23
KIF2C
SPAG5
TPX2
Spindle regulation     BUB1B ASPM
BUB1
AURKB
PLK4
PRC1
TTK
Chromosome segregation NDC80 ZWINT NUF2 BIRC5 ESPL1
SPC25 NCAPG CENPE CENPF
DSCC1 NCAPH DLGAP5  
SGOL1 KIFC1
CASC5 NUSAP1
Cytoskeleton AMPH    CKAP2L  
Nuclear membrane      LAMB1
Transcription ATAD2    MLF1IP  
CDCA7
ZNF367
Nuclear division    CDCA2 ANLN  
FAM83D CDC20
CDCA3
GTPase activator activity     DEPDC1  
DEPDC1B
ARHGAP-11A
IQGAP3
Cytokinesis     PBK RACGAP-1
ECT2
KPNA2
Membrane transport   ABCC2    
Metabolic process     HMMR CBR3
HSPH1 ELOVL6
SRD5A1
  1. Differentially expressed genes were allocated to a phase of the cell cycle by referring to phase allocations for HeLa cells [29], foreskin fibroblasts [30], immortalized keratinocytes [31] and osteosarcoma cells [32]. Functions were assigned by referring to Bar-Joseph et al.[30], the database for annotation, visualization and integrated discovery (DAVID) and Ingenuity Pathway Analysis (IPA). Table modeled after Table S3 in Additional file 2 in reference [30].