BD-L metagene values in sporadic and familial BRCA1 and BRCA2 primary tumors. BRCA1 metagene values in primary sporadic breast cancer and BRCA1 and BRCA2 primary breast cancer samples as calculated from a previously described cohort detailed in van’t Veer et al. . (A) Dot plot of individual metagene values. (B) Box plot of metagene values. A statistically significant difference in BD-L metagene value was observed for sporadic primary breast tumors when compared to mutant BRCA1 carrier primary breast tumors (P value = 0.033). BD-L, BRCA1 Deficient-Like.