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Figure 1 | Breast Cancer Research

Figure 1

From: A BRCA1deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity

Figure 1

BD-L metagene values in primary and metastatic specimens. Values in primary breast cancer and metastatic breast cancer samples as calculated from a previously described cohort detailed in Zhang et al. [29]. (A) Dot plot of individual metagene values. (B) Box plot of metagene values. Statistically significant differences in BD-L metagene value were observed for the brain metastases when compared to primary tumors (P value = 0.0043), bone metastases (P value = 4 × 10-6), and lung metastases (P value = 0.001). BD-L, BRCA1 Deficient-Like.

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