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Table 1 Frequencies of DNA methylation in the cancer tissue samples

From: Identification and characterization of locus-specific methylation patterns within novel loci undergoing hypermethylation during breast cancer pathogenesis

Loci ID

Samples availablea

Methylation-negative, n(%)

Low methylation, n(%)b

Heterogeneous methylation, n(%)

Full methylation, n(%)

Both alleles present, n(%)

TITF1

220

0 (0.0)

38 (17.3)

0

145 (65.9)

37 (16.8)

HOXB13

239

18 (7.5)

20 (8.4)

0

23 (9.6)

178 (74.5)

NR2E1

164

15 (9.1)

14 (8.5)

18 (11.0)

89 (54.3)

28 (17.1)

HTR1B

162

28 (17.3)

68 (42.0)

20 (12.3)

4 (2.5)

42 (25.9)

HMX2

187

9 (4.8)

1 (0.5)

13 (7.0)

164 (87.7)

0

BC008699

261

4 (1.5)

4 (1.5)

26 (10.0)

206 (78.9)

21 (8.0)

SLC38A4

234

0

16 (6.8)

93 (39.7)

80 (34.2)

45 (19.2)

FLJ32447

264

0

28 (10.6)

191 (72.3)

48 (18.2)

0

WT1

218

44 (20.2)

0

178 (81.7)

21 (9.6)

0

TMEM132D

218

6 (2.8)

21 (9.6)

154 (70.6)

16 (7.3)

21 (9.6)

NKX2-3

169

0

16 (9.5)

108 (63.9)

38 (22.5)

7 (4.1)

GHSR

260

56 (21.5)

24 (9.2)

180 (69.2)

0

0

ONECUT

243

0

16 (9.5)

134 (55.1)

63 (25.9)

30 (12.3)

LHX1

243

0

28 (11.5)

145 (59.7)

41 (16.9)

29 (11.9)

SIX6

246

5 (2.0)

11 (4.5)

173 (70.3)

55 (22.4)

2 (0.8)

CA10

230

21 (9.1)

48 (20.9)

137 (59.6)

24 (10.4)

0

CHR

252

0

44 (17.5)

192 (76.2)

16 (6.3)

0

POU4F

255

10 (3.9)

6 (2.4)

195 (76.5)

44 (17.3)

0

PHOX2B

256

0

3 (1.2)

199 (77.7)

53 (20.7)

1 (0.4)

  1. aVariable numbers of the samples are reported because of clinical sample limitations. bLow methylation is referred to as methylation similar to the methylation observed in control samples.